The native Tagalog word asawa is gender-neutral and can mean either husband or wife.
Filipinos informally use the English-derived misis to refer specifically to a wife.
wife
(informal word)
misis
missus
Where is the wife?
= Where is your wife?
May sakit ang misis ko.
My wife is sick.
Miss ko si misis.
I miss the missus.
(I miss my wife.)
Mahal ko ang misis ko.
I love my wife.
Da best ang misis ko!
My wife is the best!
ang maganda at mabait ko asawa
my beautiful and kind wife
Ang sabi ng asawa ko ay pogi raw ako.
My wife says I’m handsome.
Ang sabi ng asawa ko ay maganda raw ako.
My husband says I’m beautiful.
Taga-Aklan ang asawa ko.
My wife is from Aklan.
Taga-Aklan pala ang asawa niya.
Turns out his wife is from Aklan.
Magaling magluto ang asawa ko.
My wife is great at cooking.
Magaling magluto ang misis ko.
My wife is great at cooking.