At least two different meanings.

Short for kumpadre, meaning ‘friend.’

Kamusta, pare?
What’s up, dude?

Kamusta, pare?
What’s up, brother?

Mga pare ko.
My homies.

Slang version: pards

Pare can also refer to a priest, though the word in this sense can also be spelled as pari.

nangumpisal sa pare
confessed to the priest

Tanungin mo sa pari. Siya si Padre Damaso.
Ask the priest. He is Father Damaso.